LOXL2 and psychiatric disorder: Using FUMA (Functional Mapping and Annotation) and MAGMA (Multi-marker Analysis of GenoMic Annotation) pipeline, 8 protein-coding genes were identified in the 10 kb distance window, including LOXL2, ENTPD4, ADAMDEC1, ADAM7, NEFM, EBF2, BNIP3L and ADRA1A. Previous research has linked these genes to sleep related disorders, psychiatric disorders and neurodegenerative disorders (Table 2)31–38.