CTBP1 and ovarian cancer: To better understand how cell context affects CtBP regulation of DRs, we assessed the steady-state levels of DR4/5 and CtBP1/2 in a panel of additional molecularly validated HGSOC cell lines (OVSAHO, CAOV3, HEY, and OVCA429), as well as two additional reference ovarian cancer cell lines (SKOV3 and A2780) which have been used extensively in the literature but molecular studies are unable to classify31,42.