Additionally, the main molecular characteristics of BCR-ABL1-like ALL are the multiple translocations in different cytokine receptor and kinase signaling genes such as ABL1 (excluding BCR association), JAK2, ABL2, PDGFRB, TYK2, CSF1R, CRLF2, and EPOR. These mutations trigger the activation of growth promoting kinase or cytokine signaling pathways14. This evidence concerns the gene BCR and acute lymphoblastic leukemia.