CSPG4 and melanoma: On the other hand, when we investigated the tumor cell killing effects of anti-CSPG4-(PDD) in CSPG4-high expressing A375 and CSPG4-low expressing WM-1361 melanoma cells, we observed a time- and target-antigen dependent loss in proliferation in anti-CSPG4-(PDD)-exposed cells compared to PBS controls.