TNF and hypogonadism: It would also be interesting to know the length of active disease for SARS-CoV-2 patients with or without hypogonadism, since hypogonadism can worsen the systemic inflammatory response, as demonstrated on peripheral blood leukocytes where testosterone inhibits immune stimuli–induced secretion of proinflammatory cytokines, such as TNF and IFNγ [31].