To better define the macrophage’s role in atherosclerosis, we evaluated the expression of tumor necrosis factor-α (TNF-α; identified in green staining in Figure 4a,b) and of transforming growth factor-β (TGF-β; identified in green staining in Figure 4d,e), which are markers of M1 and of M2 activity, respectively. The gene discussed is TNF; the disease is atherosclerosis.