This L-NMP is similar to that sustaining Cebpa mutant neutrophil lineage leukemia (Bereshchenko et al., 2009, Kirstetter et al., 2008); however, while, NMPs normally generate only neutrophils and monocytes (Drissen et al., 2016), in the presence of both biallelic Cebpa and Gata2 ZnF1 mutations they display ectopic erythroid differentiation potential, as well as the capacity to generate bilineage L-NMPs. This evidence concerns the gene CEBPA and leukemia.