In addition to PD‐1 checkpoint ligands, melanoma cells express galectin‐1, (LGALS‐1, Gal‐1), a potent immunomodulatory lectin that favors immune escape in multiple tumors (Cedeno‐Laurent et al., 2012; Juszczynski et al., 2007; Rubinstein et al., 2004; Tang et al., 2012). This evidence concerns the gene LGALS1 and melanoma.