Overweight/obese subjects exhibited significantly lower levels of serum HDL-C in the PCOS-RPL subgroup, lower levels of FSH in the PCOS group and infertile subgroup, and higher levels of fasting insulin in the PCOS group and PCOS-inf subgroup, when compared to their normal-weight counterparts (P < 0.05 for all). This evidence concerns the gene BRD2 and Infertility.