Lin et al in 2018 reported a homozygous frameshift ZP2 (MIM: 182888) variant (p.C566Wfs*5), which truncated ZP2 C‐terminal TM domain resulting in thinner ZP, in an infertile woman (Dai, Chen, et al., 2019; Dai, Hu, et al., 2019). Here, ZP2 is linked to Infertility.