For example, LINC00470 mediated GBM cell autophagy by activating AKT.13 LncRNA HOTAIRM1 was overexpressed in GBM and promotes cell invasion and tumour growth via up‐regulating HOXA1.14 LncRNA PXN antisense RNA 1 (PXN‐AS1) was reported to be down‐regulated in pancreatic cancer cells and suppressed cancer progression.15 However, the expression of PXN‐AS1 was found to be up‐regulated in GBM tissues through GEPIA database. This evidence concerns the gene AKT1 and glioblastoma.