Furthermore, inhibition of DKK1 countervailed the suppression of Wnt/β‐catenin pathway in PXN‐AS1‐silenced GBM cells (Figure S4C‐D), further validating that PXN‐AS1 regulated Wnt/β‐catenin in GBM through targeting DKK1. The gene discussed is DKK1; the disease is glioblastoma.