Interestingly, claudin-11 KO mice also develop male sterility (Gow et al. 1999; Mazaud-Guittot et al. 2010; Morrow et al. 2010), coinciding with infertility known from adult SCCx43KO mice (Brehm et al. 2007; Sridharan et al. 2007). The gene discussed is CLDN11; the disease is Infertility.