Subjects whose genotype was TT or TG type of HTRA1 rs2293870 were more likely to develop unilateral PCV with no AMD or PCV in the contralateral eye (P = 0.040, OR = 2.917, 95% CI = 1.028–8.273; Table 3). The gene discussed is HTRA1; the disease is age-related macular degeneration.