By coating with pH-sensitive mPEG-b–PDPA20, succinobucol (SCB), vascular cell adhesion molecule-1 (VCAM-1) inhibitor could efficiently escape from micelles (PWMs) at TME, and inhibit the lung metastasis of breast cancer tumors for around ~6.25 and 4.5 times, respectively, in comparison with saline and SCB groups (He et al., 2016). Here, VCAM1 is linked to breast cancer.