For example, Petrovsky et al. synthesized a Cy5.5 conjugated Annexin V (Cy‐annexin V) probe that can be used to image cell apoptosis in gliosarcoma by using near infrared fluorescence (NIRF) imaging.[60] In this study, an active Cy‐annexin probe that bound to apoptotic Jurkat T cells was prepared and two to three times increase of NIRF signal in the treated tumor was observed with the active Cy‐annexin V probe. The gene discussed is ANXA5; the disease is neoplasm.