The researchers found that up-regulated miR-21 and miR-BART4 or down-regulated miR-143 and miR-153 in nasopharyngeal carcinoma can inhibit the apoptosis of nasopharyngeal carcinoma cells via Fas or Caspase pathway, accompanied by or not with the regulation of Bcl-2 family proteins, and the sensitivity of nasopharyngeal carcinoma cells to radiotherapy is reduced. Here, BCL2 is linked to nasopharyngeal carcinoma.