We found MyoD1, which was recently reported to performing as a transcriptor repressor in breast cancer, was the exclusive factor could be combined with both ID4 and CBF1 from STRING Interaction Network (https:// version11.string-db.org/cgi/network.pl?taskId=7z99iaiuOrw8) and Top Transcription factor binding sites by Qiagen on Genecards website (https://www.genecards.org/cgi-bin/carddisp.pl?gene=id4), respectively. The gene discussed is ID4; the disease is breast carcinoma.