For the driver gene itself, the NF1, RB1, PIK3R1, and TP53 mutants in patients demonstrated significantly lower levels of expression when compared with wild-type in GBM and lower expression levels of FUBP1, NF1, PTEN, and IDH1 in mutant patients in LGG (Figure S4). This evidence concerns the gene NF1 and glioblastoma.