Then, the improved symptoms in the WV (0.5 mg/kg) group were similar to those of the positive drug TwHF, which has been reported to inhibit the inflammatory response of RA [28], but the effect of low dose was not significant on swelling reduction and inhibition of IL-1β and TNF-α (Figures 1 and 5). The gene discussed is IL1B; the disease is rheumatoid arthritis.