Infection with RV1b increased IL-1α in non-CF (61.6 ± 31.7 pg/mL vs. 511 ± 252 pg/mL; p < 0.05) and CF AEC supernatant compared to controls (46.2 ± 32.7 pg/mL vs. 236 ± 93.1 pg/mL; p < 0.05) (Figure 2A). This evidence concerns the gene IL1A and infection.