MAPT and astrocytic tumor: For example, positive immunostaining for tau in the normal human brain and astrocytic tumors (Shin et al., 1991; Miyazono et al., 1993) and mRNA expression of tau in astrocytic tumors (Miyazono et al., 1993) have been reported, and the authors considered that astrocytes have a potential to express tau through neoplastic transformation and reactive processes (Miyazono et al., 1993).