These findings are important given the key role TIA1 plays in the pathogenesis of tauopathy, and in ALS/FTD (Apicco et al., 2017; Hirsch-Reinshagen et al., 2017; Maziuk et al., 2018; Jiang et al., 2019). The gene discussed is TIA1; the disease is amyotrophic lateral sclerosis.