IL1B and infection: Differential IL-1β induction was observed upon infection of PBMCs from IGRA+ (Fig. 3a) or IGRA– (Fig. 3b) donors, and upon infection of purified monocytes from IGRA– individuals (Fig. 3c), macrophages differentiated from the human monocytic cell line THP-1 (Fig. 3d) or mouse bone marrow-derived macrophages (BMDMs; Fig. 3e).