Meanwhile, prognostic analysis showed that the low mRNA expression of BTBD9 was positively correlated with poor prognosis in lung cancer patients (in lung adenocarcinoma: p = 0.007; in lung squamous cell carcinoma, p = 0.060, log-rank test) (Fig. 5g, h). The gene discussed is BTBD9; the disease is squamous cell lung carcinoma.