IL-6 is a cytokine of interleukins, mainly composed of antigen-presenting cells (macrophages, dendritic cells), B cells, T cells, non-hematopoietic cells such as epithelial cells, endothelial cells, astrocytes, fibroblasts, osteoblasts, mesangial cells and tumor cells [26], causing acute phase reactions of inflammation. This evidence concerns the gene IL6 and neoplasm.