In addition to direct inhibition of proliferation and necrosis of tumor cells, it also affects other cells including the growth and differentiation of cardiomyocytes also have an effect, as well as anti-virus and bacteria, activate T cells, promoted the production and secretion of IL-1, IL-2, and IL-6, induce inflammatory reactions, and promote IL-2R and epidermal growth factor receptor (EGFR). Here, IL1B is linked to neoplasm.