In terms of SS, biopsies from the conjunctiva, LG, and SG of human and SS-susceptible animal models (e.g., mouse, rat, and canine) exhibit lymphocytic infiltration with increased expression of various inflammatory and immune activation markers such as ICAM-1, LFA-1, and major histocompatibility complex class II antigens [18,19]. This evidence concerns the gene ITGAL and synovial sarcoma.