TP53 and Parkinson disease: In addition, pathways enriched in deiminated proteins in sham-treated plasma-EVs and not identified in the PD models belonged to “cell cycle”, “progesterone mediated oocyte maturation”, “Epstein Barr virus infection”, “antigen processing and presentation”, “viral carcinogenesis”, “HTLV-1 infection”, “ubiquitin mediated proteolysis”, “protein processing in ER”, “cellular senescence”, “longevity regulating pathway”, “glycolysis”, and “p53 signalling pathway” (Figure 7A).