We describe that moDCs stimulated by tumor supernatant of the highly cytotoxic NB-PDT condition are able to provide the adequate stimulatory signals for the proliferation of CD4+ T cells (Figure 6a) and differentiation towards Th1 CD4+ effector T cells, as indicated by the substantial release of IFNγ (Figure 6b). This evidence concerns the gene IFNG and neoplasm.