Lastly, to correlate our findings more clinically, we analyzed the ENG mRNA levels in patients from an online database (The Cancer Genome Atlas (TCGA) Provisional 2015) and found that a high percentage (3.72%–10.24%) of lung cancer patients had altered ENG gene expression, and in most cases, ENG was up-regulated instead of down-regulated. This evidence concerns the gene ENG and lung cancer.