Interestingly, miR-29b-3p and miR-29c-3p could suppress the expression of collagen type I α1 (COL1A1), collagen type III α1 (COL3A1) and α-SMA in mouse CF by a mechanism involving the repression of the pro-fibrosis genes TGFβ2 and MMP2. This evidence concerns the gene ACTA1 and cystic fibrosis.