MAPT and amyotrophic lateral sclerosis: Accordingly, these observations led to a different Innotest Amyloid Tau Index (IATI) index between controls and ALS patients (controls: 1.69 ± 0.62, ALS: 2.32 ± 0.66; p < 0.0001), and an increased ratio Aβ1-42/phosphorylated-Tau (phospho-Tau) (controls: 24.3 ± 11.6; ALS: 31.2 ± 9.8; p < 0.0001).