The mRNA expression of BDNF and ciliary neurotrophic factor (CNTF) in PC12 cells was lower in the AD-Con group than the Normal-Con group, and the high dosage of TTK-E and TTK-W prevented the decrease in BDNF and CNTF by amyloid-β(25–35) (Figure 1B,C). The gene discussed is BDNF; the disease is Alzheimer disease.