RHAG and asthma: Comparing the anti-allergic activities of naïve ginsenosides Rb1, Rg3, and Re to those of their metabolite ginsenosides CK, Rh2, and Rh1, metabolites (ginsenosides CK, Rh2, and Rh1) suppress allergic reactions such as passive cutaneous anaphylaxis, scratching, and asthma more potently than parental ginsenosides Rb1, Rg3, and Re, respectively [38,62,81,82,93].