Many bispecific antibodies bind to CD3 of the TCR and to an antigen on the cancer cells, e.g., EpCAM on carcinomas such as breast and prostate cancer (Catumaxomab and Solitomab), Her/neu on breast cancer cells (Ertumaxomab), PSMA on prostate cancer cells (Pasotuxizumab), or BCMA (B cell maturation antigen) on myeloma cells (AMG420) [333]. The gene discussed is ERBB2; the disease is breast carcinoma.