PROM1 and hepatocellular carcinoma: Having shown that the oncogenic activity of MALAT1 in HCC is associated with enhanced expression of pluripotency markers CD133 and ALDH1, and is mediated, at least in part, by the Wnt/β-catenin signaling pathway, in vitro, we further investigated the translational relevance of these findings in the context of current anticancer chemotherapy, and in in vivo murine HCC models.