MALAT1 and hepatocellular carcinoma: Similarly, using different human HCC cell lines, we demonstrated that compared to its expression in the epitheloid well-differentiated Huh7 cell (1.5-fold, p < 0.01), the expression of MALAT1 was profoundly enhanced in the fibroblastoid poorly-differentiated Mahlavu (1.7-fold, p < 0.01) and HepG2 human hepatoblastoma cell lines (2.6-fold, p < 0.001), SK-Hep1 (2.8-fold, p < 0.001) HCC cell lines [14], and markedly low expression in the normal liver THLE-2 cell line (0.2-fold, p < 0.001) (Figure 1B).