Consistent with the above, results of our comparative analyses of paired HCC and adjacent non-tumor tissue samples (n = 8 pairs) from the Taipei Medical University-Shuang-Ho Hospital patients cohort (n = 72) using the quantitative PCR demonstrate that the expression of MALAT1 is enhanced in most (~75%) HCC samples compared to their non-tumor counterpart, with a mean expression which is 2.66-fold higher in the HCC in comparison to the non-tumor group (p < 0.01) (Figure 1C). Here, MALAT1 is linked to hepatocellular carcinoma.