We observed that the expression of MALAT1 was highest in HCC, compared to other pathological liver conditions or normal liver; compared to the normal liver samples, MALAT1 expression in the HCC and liver cell dysplasia samples was up-regulated by 3.23-fold (p = 1.38 × 10−6; t-test = 6.28), and 3.17-fold (p = 2.59 × 10−6; t-test = 6.28), respectively (Figure 1A). This evidence concerns the gene MALAT1 and hepatocellular carcinoma.