PROS1 and esophageal varices: Univariate analysis showed that platelet count ≤100 × 103/uL (p = 0.051, hazard ratio (HR) = 1.66, 95% CI = 0.99–3.94), protein C deficiency (p = 0.017, HR = 3.22, 95% CI = 1.23–8.41), protein S deficiency (p = 0.005, HR = 2.82, 95% CI = 1.66–5.84), and presence of esophageal varices (p = 0.037, HR = 2.19, 95% CI = 1.05–4.56) were the significantly different factors between the two groups.