In addition to CM, the tumor spectrum of BAP1 pathogenic variants includes uveal melanoma (UM), mesothelioma, basal cell carcinoma (BCC), renal cell carcinoma (RCC), and BAP1-inactivated melanocytic tumors (BIMTs), which together constitute the BAP1-tumor predisposition syndrome (BAP1-TPDS) [27]. The gene discussed is BAP1; the disease is hereditary clear cell renal cell carcinoma.