Additionally, more recently, some other indices that were basically computed by serum albumin level and lymphocyte count, such as the Prognostic Nutritional Index (PNI) and Controlling Nutritional Status (CONUT) score, have also been shown to have prognostic value in patients with HF, and more precisely assessed the prognostic values of malnutrition on long-term clinical outcomes in patients with HF [20,21]. The gene discussed is ALB; the disease is malnutrition.