On the basis of the above-mentioned bioinformatics analysis and considering that the IGF-1R-mediated signaling in cancer may involve FAK [48,49,50], we investigated whether the IGF-1/IGF-1R transduction pathway may lead to FAK phosphorylation in MDA-MB 231 and SUM159 cells that were used as a model system for TNBC. Here, IGF1R is linked to cancer.