CSF2 and neoplasm: A study of the mechanism showed that T-MDSCs but not splenic MDSCs increase lipid uptake, which reveals that the fatty acid translocase CD36, induced by tumor-derived cytokines (G-CSF and GM-CSF) and targeted by the STAT3 and STAT5 signaling pathways, is relevant to FAO and immunosuppression of T-MDSCs [78].