Although batimastat is not specific to MMP2 and MMP9 and also inhibits MMP1, MMP3, MMP7, MMP8 and several ADAM family members, based on the gelatin zymography of tumor samples before and after treatment, it was hypothesized that the tumor-inhibiting effect of batimastat was dependent on MMP2 and, to a lesser extent, MMP9. The gene discussed is MMP2; the disease is neoplasm.