TLR4 and Alzheimer disease: The relationship of TLRs polymorphisms with AD, i.e., TLR2 rs55743708(G>A) and TLR4 rs4986790(A>G) were reported to increase levels of IL-4 and IL-10 in Russian AD patients [61], while other authors found no association of TLR2 polymorphisms, i.e., rs5743708 and rs4696480, in Turkish children with AD [69].