Additionally, 17 of the new AD identified genes could not be ascribed to significant biological functions, i.e., CARD14, CRNN, TCHHL1, RPTN, PANX3, PHLDB1, LILRA6, NLRP2, MTF1, LTA, MAST2, DOCK8, CUX2, ADCY10, VSTM1, and RTEL1. This evidence concerns the gene CUX2 and Alzheimer disease.