This might be the cases of CARD14, with similar functions to CARD11 [163]; VSTM1, which behaves as a cytokine [164]; LILRA6, a member of the leukocyte immunoglobulin-like receptor family [165]; mutations in DOCK8 are responsible for an immunodeficiency syndrome [166]; NLRP2 is involved in inflammatory processes [167,168]; RTEL1, a helicase involved in telomere maintenance, has also been found associated to severe dyskeratosis congenita [169]; LT-α (also known as TNF-β), which is a cytokine produced by lymphocytes [170]. The gene discussed is DOCK8; the disease is dyskeratosis congenita.