CCR7 and Alzheimer disease: When comparing the lesional tissue of AD patients with normal skin samples of healthy controls, Yang et al. described miR-124 downregulation in AD lesional tissue [25] and in an in silico interaction analysis of differentially expressed miRNAs, Li et al. [32] postulated that downregulation of hsa-let-7a-5p would potentially upregulate CCR7, a chemokine receptor involved in the activation of T cells [105].