Compared with control rats receiving scramble RNA, the levels of miR‐483 in sera and lung were decreased, while the mRNA and protein levels of PAH‐related genes (e.g., TGF‐β, TGFBR2, β‐catenin, CTGF, IL‐1β, and ET‐1) were upregulated in rats having LNA‐483 (Appendix Fig S5A–C). The gene discussed is EDN1; the disease is pulmonary arterial hypertension.