Then, recent review mentioned as follow: IgA1 antibodies in IgAV are generated against autoantigens on endothelial cells, such as infection-related microorganisms or β2GPI, and such anti-endothelial IgA1 antibodies (AECA) ultimately induce vessel damage via infiltration of neutrophils [2, 49]. The gene discussed is IGHA1; the disease is infection.