Potential associations between the MAGS subtypes and well-documented mutations in seven AML-associated oncogenes recorded for both the TCGA and the GSE6891 cohort (CEBPA, FLT3 [including both the FLT3-itd and FLT3-tkd aberrations], IDH1, IDH2, KRAS, NPM1, and NRAS) were investigated in the meta-cohort. The gene discussed is NPM1; the disease is acute myeloid leukemia.