In particular, PAK4, which regulates cell adhesion [34] and apoptosis [32], is of interest in this context given the known effects on cell growth and/or metastasis by Ang-(1–7)/Mas1 in nasopharyngeal carcinoma [67], prostate cancer [68,69], breast cancer [70], and other cancers [71]. This evidence concerns the gene MAS1 and breast cancer.