Small nucleolar RNA host gene 16 (SNHG16) belongs to long noncoding RNA (lncRNA) family, and has been proved to be associated with the tumorigenesis of many cancer types,9, 10 moreover, lncRNAs act frequently as a tumor suppressor or promoter of the activation of oncogene.11, 12. The gene discussed is SNHG16; the disease is neoplasm.