EGR1 expression was determined in tumor cells (Figure 10C‐E), sorafenib and si‐SNHG16 were found to significantly increase the EGR1 expression (P < .001), whereas the transfection of miR‐23b‐3p inhibitor significantly reduced the EGR1 expression (P < .001). The gene discussed is EGR1; the disease is neoplasm.