Table 3 shows that the factors highly associated with pronouncedly shorter overall survival time were as following: serum DKK‐1 levels above 3.7 ng/ml, unreactive pupils, acute traumatic coagulopathy, acute lung injury, progressive hemorrhagic injury, post‐traumatic cerebral infarction, age, midline shift > 5 mm, blood leukocyte count, serum C‐reactive protein levels, blood glucose levels, admission GCS scores, and Rotterdam CT classification (all p < .05). This evidence concerns the gene DKK1 and brain infarction.