IL1RL1 and asthma: While we present a comprehensive analysis of functional effects of IL1RL1 region SNPs for IL1RL1 gene expression and function, we acknowledge that functional effects on other genes ( eQTL effects on IL18R1, for example) may be of relevance, as well; however, these were beyond the focus of our current investigations to advance our understanding of the contribution of genetic variants to IL1RL1 biology in the context of asthma.