RUNX1 is frequently involved in chromosomal translocations observed in acute leukaemias, such as ETV6‐RUNX1 in t(12;21) and RUNX1‐EVI1 in t(3;21),19 while the formation of the chimeric protein RUNX1‐CBF2T1 (AML1‐ETO) is associated with the M2 subtype of acute myeloid leukaemia (AML).20, 21. This evidence concerns the gene ETV6 and acute myeloid leukemia.